argenx Expands Capabilities In Antibody Engineering Through Key Technology Partnerships
October 06, 2020 at 02:00 AM EDT
October 6, 2020
“Our Immunology Innovation Program, through which we partner with leading academic researchers, has been foundational in building our pipeline. In keeping with our commitment to expand and strengthen this program, we continue to make investments in our portfolio of antibody technologies. These new partnerships are a key part of the strategy to broaden our capabilities in antibody engineering in order to address new targets and develop first-in-class medicines for patients who need them,” commented Hans de Haard, Ph.D., Chief Scientific Officer of argenx. “Additionally, we announced the extension of our collaboration with Halozyme to secure our ability to offer subcutaneous delivery of current and future pipeline candidates. We are on a mission to improve the lives of people suffering from severe autoimmune diseases and cancer and believe that this long-term collaboration will allow us to reach the greatest number of patients.”
New Antibody Engineering Research Agreements
argenx has entered into two new research agreements to broaden its antibody engineering capabilities. Through these agreements, argenx can access world-class Fc engineering technologies to expand the therapeutic properties of future antibody candidates that emerge from its Immunology Innovation Program. The technologies will complement argenx’s current portfolio of Fc engineering technologies (NHANCE®, ABDEG™, POTELLIGENT®) and enable the Company to further differentiate and expand its pipeline of antibody candidates.
Expansion of Access to Halozyme’s ENHANZE® Technology
argenx and Halozyme are expanding the existing global collaboration and license agreement that was signed in February 2019. Under the newly announced expansion, argenx gained the ability to access Halozyme’s ENHANZE® drug delivery technology for three additional exclusive targets upon nomination bringing the total to six potential targets under the collaboration. To date, two targets have been nominated including the human neonatal Fc receptor FcRn and complement component C2.
ENHANZE® has demonstrated across five FDA-approved products the ability to remove traditional limitations on the volume of biologics that can be delivered subcutaneously, potentially shortening drug administration time, reducing healthcare practitioner time, and offering additional flexibility and convenience for patients.
For more information about innovation at argenx, please visit the Company’s website at www.argenx.com/innovation.
The contents of this announcement include statements that are, or may be deemed to be, “forward-looking statements.” These forward-looking statements can be identified by the use of forward-looking terminology, including the terms “believes,” “estimates,” “anticipates,” “expects,” “intends,” “may,” “will” or “should” and include statements argenx makes concerning the intended benefits of its partnerships and the therapeutic potential of its product candidates. By their nature, forward-looking statements involve risks and uncertainties and readers are cautioned that any such forward-looking statements are not guarantees of future performance. argenx’s actual results may differ materially from those predicted by the forward-looking statements as a result of various important factors, including argenx’s expectations regarding its the inherent uncertainties associated with competitive developments, preclinical and clinical trial and product development activities and regulatory approval requirements; argenx’s reliance on collaborations with third parties; estimating the commercial potential of argenx’s product candidates; argenx’s ability to obtain and maintain protection of intellectual property for its technologies and drugs; argenx’s limited operating history; and argenx’s ability to obtain additional funding for operations and to complete the development and commercialization of its product candidates. A further list and description of these risks, uncertainties and other risks can be found in argenx’s U.S. Securities and Exchange Commission (SEC) filings and reports, including in argenx’s most recent annual report on Form 20-F filed with the SEC as well as subsequent filings and reports filed by argenx with the SEC. Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements. These forward-looking statements speak only as of the date of publication of this document. argenx undertakes no obligation to publicly update or revise the information in this press release, including any forward-looking statements, except as may be required by law.
For further information, please contact:
Beth DelGiacco, Vice President, Investor Relations (US)
Joke Comijn, Director Corporate Communications & Investor Relations (EU)